Endocrine Abstracts

Endometriotic tissues express oestrogen receptors and depend on oestrogen to proliferate, survive and cause symptoms, such as deep neuropathic pain, by recruiting neurones into the tissue. Raloxifene is an anti-oestrogen and so may prevent many of these effects and although the effect of raloxifene on endometriosis has not been directly assessed, low-dose use in a recent trial has been associated with a rapid return of pain symptoms. In this pilot study, pre-menopausal women w...